Title

Basic Information
Predicted Impact on Human Body
Basic Information
BGC Name(-)-Mellein biosynthetic gene cluster
MicrobeParastagonospora nodorum
Metabolite(-)-Mellein
Predicted Impact on Human Body
Side Effect
NameScore
Hepatic cancer metastatic 0.4464
Localized exfoliation 0.4872
Abnormal withdrawal bleeding 0.4872
Cardiovascular disorder 0.4464
Scrotal erythema 0.4464
Immunodeficiency 0.4464
Weight fluctuation 0.4872
Cervical discharge 0.4872
Retinitis 0.4464
Cardiotoxicity 0.4464
Cachexia 0.4464
Mucous membrane disorder 0.4464
Ventricular arrhythmia 0.4464
Metastases to liver 0.4464
Potential Indication
DescriptionScore
Currently Genistein is being studied in clinical trials as a treatment for prostate cancer.0.6774
Trioxsalen is a pigmenting photosensitizing agent used in conjunction with ultraviolet light in the treatment of vitiligo.0.6452
For lowering cholesterol and, possibly, otherwise favorably affecting lipids. <i>In vitro</i> research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase activity, as well as activity again.0.7059
For diagnostic imaging. Primarily indicated in diagnostic fluorescein angiography or angioscopy of the fundus and of the iris vasculature.0.6667
Used for the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).0.8276
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.0.8667
Used for the control of nausea and vomiting, caused by chemotherapeutic agents used in the treatment of cancer, in patients who have failed to respond adequately to conventional antiemetic treatments.0.6211
Ellagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines.0.6667
For the treatment of psoriasis and vitiligo0.6364
For decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis.0.6667
Impact on Immune System
Immune Status TransitionCellTissuep valueScore
Tgd.vg1+vd6+.Th.TCRbko-Tgd.vg1+vd6+24ahi.Th.TCRbkoTgdthymus1e-180.4370
T.8Eff.Sp.OT1.d6.LisOva-T.8Eff.Sp.OT1.d15.LisOvaT8spleen1e-180.4515
T.8Eff.Sp.OT1.d5.VSVOva-T.8Eff.Sp.OT1.d6.VSVOvaT8spleen1e-180.4760
T.8Eff.Sp.OT1.d6.LisOva-T.8Eff.Sp.OT1.d8.LisOvaT8spleen1e-180.4411
T.8Eff.Sp.OT1.d6.LisOva-T.8Eff.Sp.OT1.d8.LisOvaT8spleen6.4615e-180.4557
T.8Eff.Sp.OT1.d6.LisOva-T.8Eff.Sp.OT1.d15.LisOvaT8spleen2.26152e-170.4557
T.8Eff.Sp.OT1.d5.VSVOva-T.8Eff.Sp.OT1.d15.VSVOvaT8spleen1e-180.4315
T.8Nve.MLN-T.8Nve.SpT8spleen1e-180.4622
T.8Eff.Sp.OT1.d5.VSVOva-T.8Eff.Sp.OT1.d6.VSVOvaT8spleen1e-180.4924
T.8Eff.Sp.OT1.d5.VSVOva-T.8Eff.Sp.OT1.d15.VSVOvaT8spleen1.2923e-170.4252